[Pyr1]-Apelin 13

[Pyr1]-Apelin 13

Catalog Number:
P004516765LIF
Mfr. No.:
PEPTIDE-AR-020
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  • Size:
    1mg
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      • Overview

        • Endogenous agonist for the apelin APJ receptor.
          [Pyr1]-Apelin 13 or [pGlu1]-apelin-13 is a highly potent pyroglutamyl form of apelin 13 which acts as the endogenous ligand for the apelin APJ receptor, with an EC50 of 0.37 nM. [Pyr1]-Apelin 13 is the predominant isoform detected in human heart and plasma and acts as a potent inotropic agent and vasodilator.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          [Pyr1]-Apelin 13, [pGlu1]-apelin-13
          Molecular Formula
          C69H109N22O16S
          Molecular Weight
          1533.8
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in dilute acid and physiological buffers
          Other Properties
          Sequence: Glp-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH,XRPRLSHKGPMPF
          Modification: X is pGlu
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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