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Overview
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Serine346 (S346) is a major phosphorylation site of the nociceptin/orphanin FQ peptide receptor (NFQ receptor, NOP). The pS346-NOP antibody detects phosphorylation in response to agonists as well as after PKC activation. S346 phosphorylation is a key regulator of NOP desensitization, β-arrestin recruitment and internalization.
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- Properties
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Overview