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PROTAC Linker 4

PROTAC Linker 4

Catalog Number:
PTC1441482INV
Mfr. No.:
V4743
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      • Overview

        • PROTAC Linker 4 is a non-peptide (small molecule) linker used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs). Small molecule-induced protein degradation is an attractive strategy for the development of chemical probes. One method for inducing targeted protein degradation involves the use of PROTACs, heterobifunctional molecules that can recruit specific E3 ligases to a desired protein of interest. PROTACs have been successfully used to degrade numerous proteins in cells, but the peptidic E3 ligase ligands used in previous PROTACs have hindered their development into more mature chemical probes or therapeutics.

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      • Properties
        • Categories
          PROTAC Linkers
          CAS Number
          1799506-30-1
          Molecular Formula
          C16H31CLO7
          Molecular Weight
          370.87
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          ClCCCCCCOCCOCCOCCOCCOCC(O)=O

          * For research use only

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