Prodigiosin

- Overview
  - Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant in 2007.
    
    Prodigiosin is soluble in ethanol, methanol, DMF and DMSO.
    
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    Background
    
    Prodigiosin acts via caspase inhibition to induce of apoptosis in human primary cancer cells. Prodigiosin also acts as an inducer of p21WAF1/CIP1 expression via transforming growth factor-β receptor pathway, and activates NAG-1 via glycogen synthase kinase-3β.
- Properties
  - CAS Number
    
    82-89-3
    
    Molecular Formula
    
    C20H25N3O
    
    Molecular Weight
    
    323.4
    
    Appearance
    
    Dark red solid
    
    Storage
    
    -20°C
    
    * For research use only