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Overview
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T4 DNA Ligase catalyzes the formation of a phosphodiester bond between the 5'-phosphate and 3'-hydroxyl termini of adjacent nucleotides in double-stranded DNA or RNA with either cohesive or blunt ends. This reaction requires ATP as a cofactor. Additionally, T4 DNA Ligase can repair single-strand nicks in double-stranded DNA, double-stranded RNA, or DNA/RNA hybrids.
Features
• Excellent Heat Stability: Maintains over 60% residual activity after 4 hours at 42°C.
• Ultra-Low Adapter Self-Ligation: Cleaner Libraries, Higher Sensitivity
• Excellent batch-to-batch consistency: Stable and uniform performance.Please contact us at for specific academic pricing.
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- Properties
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Overview
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