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PRAS40 Rabbit mAb

PRAS40 Rabbit mAb

Catalog Number:

A001548844RED

Mfr. No.:

RDSA65420

Price:

$470

Size:

100μL

Quantity:

Add to Cart:

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthesized peptide derived from human PRAS40
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Molecular Weight
  
  40kDa (Calculated)
  
  Antigen
  
  40 kDa proline rich AKT substrate;AKT1 S1;AKT1 substrate 1 (proline rich);AKT1S1;Lobe;PRAS40;Proline rich akt substrate (UniProt:Q96B36)
  
  * This product is for Research Use Only.

Applications

Application

WB; IHC; IP; FC

Application	Dilutions
WB	1:500-1:2000
IHC	1:50-1:200
IP	1:50
FC	1:50

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