PKI (14-22) amide, myristoylated

PKI (14-22) amide, myristoylated

Catalog Number:
P004516699LIF
Mfr. No.:
PEPTIDE-KS-110
Price:
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Cell permeable protein kinase A inhibitor.
          PKI (14 – 22) amide, myristoylated, is a cell-permeable version of the protein kinase inhibitor (PKI) PKI (14-22) amide. When non-myristoylated, PKI (14-22) amide inhibits protein kinase A with a Ki of 36 nM and also inhibits cell growth and induces apoptosis in human pancreatic cancer cells (PANC-1). Myristoylated peptides as a class may exhibit off-target activation of the funny current If in sinoatrial myocytes.

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      • Properties
        • Categories
          Cell Penetrating Peptides
          Molecular Formula
          C53H100N20O12
          Molecular Weight
          1209.5
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in dilute acid and DMSO as a stock solution.
          Other Properties
          Sequence: Myr-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2,Myr-GRTGRRNAI-NH2
          Modification: Myristoyl at N terminal, amide at C terminal
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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