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Pirarubicin

Pirarubicin

Catalog Number:
A004364301APE
Mfr. No.:
APE-B2295
Price:
$180
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      • Overview

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          Background

          Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication. Pirarubicin is an inhibitor of Topo II.

      • Properties
        • Categories
          Topoisomerase II inhibitor; anthracycline antibiotic
          Alternative Name
          7-[4-amino-6-methyl-5-(oxan-2-yloxy)oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
          CAS Number
          72496-41-4
          Molecular Formula
          C32H37NO12
          Molecular Weight
          627.64
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; insoluble in EtOH; ≥7.65 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6

          * For Research Use Only

      • Reference

        • 1. Krai Daowtak,Suchart Kothan,et al. "In vitro evaluation of P-glycoprotein functions in human neuroblastoma cell lines." Journal of Associated Medical Sciences.Vol 51 No 2 (2018): May-August.

    Documents

    COA (Certificate Of Analysis)

    MSDS (Material Safety Data Sheet)

    Datasheet

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