Phosphocreatine disodium salt

Phosphocreatine disodium salt

Catalog Number:
FC01366193APE
Mfr. No.:
APE-B7648
Price:
$204
  • Size:
    5g
    Quantity:
    Add to Cart:
      • Overview
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          Background

          Phosphocreatine (also known as creatine phosphate) disodium salt is a phosphorylated creatine molecule that may serve as a quickly accessible reserve of high-energy phosphates in skeletal muscle, myocardium as well as the brain. Phosphocreatine can offer a phosphate group to ADP for ATP synthesis, or conversely, excess ATP can be used to convert creatine to creatine phosphate via creatine kinase. Thus, phosphocreatine disodium salt could be used as a substrate for the determination of creatine kinase, and is used to regenerate ATP during skeletal muscle contraction.

          1. Wallimann T, Wyss M, Brdiczka D, et al. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochemistry Journal, 1992, 281: 21-40.
          2. Feldman EB. Creatine: a dietary supplement and ergogenic aid. Nutrition Reviews, 1999, 57(2): 45-50.
          3. Qaed E, Wang J, Almoiliqy M, et al. Phosphocreatine improves cardiac dysfunction by normalizing mitochondrial respiratory function through JAK2/STAT3 signaling pathway in vivo and in vitro. Oxidative Medicine and Cellular Longevity, 2019, 2019: 6521218.

      • Properties
        • Categories
          A phosphate reservoir used to regenerate ATP during skeletal muscle contraction
          Alternative Name
          sodium (E)-(amino((carboxymethyl)(methyl)amino)methylene)phosphoramidate
          CAS Number
          922-32-7
          Molecular Formula
          C4H8N3Na2O5P
          Molecular Weight
          255.08
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in ETOH; insoluble in DMSO; ≥54.6 mg/mL in H2O
          Storage
          Store at -20°C
          SMILES
          OC(CN(C)/C(N)=N/P([O-])([O-])=O)=O.[Na+].[Na+]

          * For Research Use Only

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