Phomopsin A

Phomopsin A

Catalog Number:
CR04341386TOK
Mfr. No.:
TOK-P080
Price:
$486
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      • Overview
        • Phomopsin A is a an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids linked in an ansa macrocycle with a tripeptide tail, terminating in a dicarboxylic acid. Phomopsin A is a potent mycotoxin produced by the fungus, Phomopsis leptostromiformis, and causes lupinosis in livestock fed infected lupins. Phomopsin A is an important bioprobe for understanding cellular structural proteins.

          Phomopsin A is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

          Please contact us at for specific academic pricing.

          Background

          Phomopsin A binds selectively to dimeric tubulin at a site overlapping that of vinblastine and maytansine, inhibiting the formation of the microtubule spindle to block cell division. Uniquely, phomopsin A protects tubulin from decay.

      • Properties
        • CAS Number
          64925-80-0
          Molecular Formula
          C36H45ClN6O12
          Molecular Weight
          789.2
          Appearance
          White solid
          Storage
          -20°C

          * For research use only

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