Pep2-8

Pep2-8

Catalog Number:
P004516895LIF
Mfr. No.:
PEPTIDE-OP-020
Price:
$239
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • PCSK9 inhibitor.
          Pep2-8 is a peptide from a phage library that was identified as the smallest proprotein convertase subtilisin/kexin type 9 (PCSK9 inhibitor) with a clearly defined mechanism of inhibition. Pep2-8 binds to PCSK9 with a KD of 0.7 μm but has no affinity for other proprotein convertases. Pep2-8 restores low density lipoprotein (LDL) receptor function and LDL uptake in PCSK9-treated HepG2 cells.

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      • Properties
        • Categories
          Peptides
          Molecular Formula
          C83H110N16O24
          Molecular Weight
          1715.88
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 2 mg/ml in PBS
          Other Properties
          Sequence: Ac-Thr-Val-Phe-Thr-Ser-Trp-Glu-Glu-Tyr-Leu-Asp-Trp-Val-NH2,Ac-TVFTSWEEYLDWV-NH2
          Modification: N-terminal Ac, C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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