PDLIM7 Mouse Monoclonal Antibody

PDLIM7 Mouse Monoclonal Antibody

Catalog Number:
A001452212ZEN
Mfr. No.:
Zen-222596
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    • Overview
      • Please contact us at for specific academic pricing.

        Background

        The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

    • Properties
      • Host
        mouse
        Isotype
        Mouse IgG1
        Reactivity
        human
        Immunogen
        Purified recombinant fragment of human PDLIM7 expressed in E. Coli.
        Purification
        Affinity Purified
        Conjugate
        Unconjugated
        Formulation
        Purified antibody in PBS with 0.05% sodium azide
        Storage
        Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
        Antigen
        (Gene ID:9260; UniProt:Q9NR12)

        * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

    • Applications
      • Application
        IHC-P; ICC/IF; FC; ELISA
      • Application Dilutions
        IHC 1/100-1/200
        IF 1/50-1/200
        FC 1/50-1/100
        ELISA 1/10000