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Overview
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Background
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. Phosphorylation of Thr229 in the catalytic domain and Thr389 in the linker domain are most critical for kinase function. Phosphorylation of Thr389, however, most closely correlates with p70 kinase activity in vivo. Prior phosphorylation of Thr389 is required for the action of phosphoinositide 3-dependent protein kinase 1 (PDK1) on Thr229.
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- Properties
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Overview
p70 S6 Kinase Rabbit mAb
p70 S6 Kinase Rabbit mAb
Catalog Number:
A001548724RED
Mfr. No.:
RDSA65300
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.