p-mHMG1tag plasmid

- Overview
  - Plasmid p-HMG1tag is derived from plasmid p-mHMG1, and expresses mouse HMGB1 containing the HA epitope, for detection with anti-HA monoclonal antibody (Falciola et al. High mobility group 1 protein is not stably associated with the chromosomes of somatic cells. J Cell Biol 1997, 137: 19-26).
    
    Mouse HMGB1 contains only 2 conservative substitutions with respect to human HMGB1.
    When transfected in mammalian cells, this plasmid increases transiently the HMGB1 content 4- to 7-fold.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Plasmids
    
    * This product is intended for research only, and cannot be used on humans.
- Reference
  - The Regulatory Role of Nuclear Respiratory Factor 1 in Bladder Cancer Cells
    CUL4A-mediated ZEB1/microRNA-340-5p/HMGB1 axis promotes the development of osteoporosis
    Leukoreduced PRP enhanced proliferation and ECM production yet inhibited senescence, inflammation, and multi-differentiation potential of AFSCs by downregulating HMGB1
    HSF1 enhances the attenuation of exosomes from mesenchymal stem cells to hemorrhagic shock induced lung injury by altering the protein profile of exosomes
    The Role of Box A of HMGB1 in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-aging Therapy
    Determination of the Impact of High-Intensity Pulsed Electromagnetic Fields on the Release of Damage-Associated Molecular Pattern Molecules
    Afzelin induces immunogenic cell death against lung cancer by targeting NQO2
    Evidence for SIRT1 Mediated HMGB1 Release From Kidney Cells in the Early Stages of Hemorrhagic Shock
    The Anti-inflammatory Effects of HMGB1 Blockades in a Mouse Model of Cutaneous Vasculitis
    Nonoxid-HMGB1 Attenuates Cognitive Impairment After Traumatic Brain Injury in Rats
    Calogero et al. The lack of chromosomal protein HMG1 does not disrupt cell growth, but causes lethal hypoglycaemia in newborn mice. Nature Genet 1999, 22: 276-80.
    Aidinis et al. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate Recombination Signal Sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2. Mol Cell Biol 1999, 19: 6532-42.