Name: Oxytetracycline ReadyMade Solution
Price: 276.00 USD

- Overview
  - Oxytetracycline ReadyMade™ Solution is a sterile-filtered (0.22 μm) solution of Oxytetracycline Hydrochloride that has been dissolved in water at a concentration of 1 mg/ml.
    
    Oxytetracycline is a broad-spectrum tetracycline that was discovered near the Pfizer laboratories in a soil sample containing Streptomyces rimosus by Finlay et al., in 1950. Together with the chemist Robert B Woodward, they deciphered the chemical structure which allowed Pfizer to produce it commercially under the trade name Terramycin. Oxytetracycline can be used for studying the oxytetracycline-resistance gene (otrA).
    
    Please contact us at for specific academic pricing.
- Properties
  - CAS Number
    
    2058-46-0
    
    Molecular Formula
    
    C22H24N2O9•HCl
    
    Molecular Weight
    
    496.89
    
    Appearance
    
    Clear solution
    
    Other Properties
    
    Mechanism of Action: The mechanism of Oxytetracycline involves diffusing through a cell and binding to the 30s ribosomal subunit preventing peptide elongation and ultimately inhibiting protein synthesis. Resistance to Oxytetracycline can be a result of inactivation by cell enzymes or pumping the antibiotic out of the cell upon entering.
    
    Storage
    
    -20°C
    
    * For Research Use Only,
- Applications
  - Application Description
    
    Spectrum: Oxytetracycline is a broad-spectrum antibiotic which targets Gram-positive and Gram-negative species as well as a few Mycoplasma species
    
    Microbiology Applications:
    Oxytetracycline is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive, Gram-negative, and Mycoplasma microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options.
    
    Representative MIC values include:
    • Haemophilus influenzae 1.6 µg/mL – 6.3 µg/mL
    • Mycoplasma bovis 0.12 µg/mL - 4 µg/mL
    • For a representative list of Oxytetracycline MIC values, click here.
    
    Media Supplement
    Oxytetracycline is used as a selective agent in OGYE, a selective media for yeasts and molds.
    
    Plant Biology Applications:
    Oxytetracycline has been used to prevent fire blight in apple and pears in the Pacific Northwest region of the USA. In a study by Hubbard et al., Oxytetracycline was shown to be a better alternative to streptomycin to inhibit fire blight disease.
- Reference
  - Chopra I and Roberts M (2001) Tetracycline Antibiotics: Mode of action, applications, molecular biology, and epidemiology of bacterial resistance." Microbio. and Molec. Biol. Rev. 232-60.
    
    Hubbard AR (2011) Evaluation of Kasugamycin-use strategies designed to delay development of resistance in Erwinia amylovora. Mastes thesis. Botany and Plant Pathology, Oregon state University.

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Oxytetracycline ReadyMade Solution

Oxytetracycline ReadyMade Solution

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