NNGH

NNGH

Catalog Number:
P004516997LIF
Mfr. No.:
PEPTIDE-PI-060
Price:
  • Size:
    5mg
    Quantity:
    Add to Cart:
      • Overview
        • Matrix metalloproteinase 3 (MMP-3) inhibitor.
          NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3, stromelysin 1, progelatinase). Inhibition of MMP-3 with NNGH significantly suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-KB, AP-1, and MAPK in LPS-stimulated microglia, suggesting a role for MMP-3 in neuroinflammation. NNGH additionally shows broad spectrum inhibition activity at other MMPs and is cell permeable.

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      • Properties
        • Categories
          Small Molecules
          Molecular Formula
          C13H20N2O5S
          Molecular Weight
          316.37
          Appearance
          Off white solid
          Purity
          >98%
          Solubility
          Soluble in DMSO to 100 mM and in ethanol to 25 mM
          Other Properties
          Sequence: N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic acid,N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic acid
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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