NFAT Inhibitor

NFAT Inhibitor

Catalog Number:
L002369290APE
Mfr. No.:
APE-A4539
Price:
$212
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
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          Background

          Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells.

      • Properties
        • Alternative Name
          (S)-2-((Z)-((S)-2-((Z)-((S)-2-((Z)-(((S)-1-((1Z,3S,4Z,6S,7Z,9S,10Z,12S,13Z,15S,16Z)-1-((S)-1-((S)-2-((Z)-(((S)-1-(2-((Z)-((S)-2-((Z)-((S)-2-amino-1-hydroxy-4-(methylthio)butylidene)amino)-1-hydroxypropylidene)amino)acetyl)pyrrolidin-2-yl)(hydroxy)methylen
          CAS Number
          249537-73-3
          Molecular Formula
          C75H118N20O22S
          Molecular Weight
          1683.93
          Appearance
          A lyophilized powder
          Purity
          98.00%
          Solubility
          insoluble in EtOH; ≥179.9 mg/mL in DMSO with ultrasonic; ≥34.54 mg/mL in H2O with ultrasonic
          Storage
          Store at -20°C

          * For Research Use Only

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