NB-598

NB-598

Catalog Number:
L002368776APE
Mfr. No.:
APE-A3645
Price:
$444
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      • Overview
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          Background

          NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

      • Properties
        • Alternative Name
          NB 598;NB598; (E)-N-(3-([3,3'-bithiophen]-5-ylmethoxy)benzyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine
          CAS Number
          131060-14-5
          Molecular Formula
          C27H31NOS2
          Molecular Weight
          449.67
          Appearance
          A brown oil
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥49.3 mg/mL in EtOH with gentle warming; ≥54 mg/mL in DMSO with gentle warming
          Storage
          Store at -20°C

          * For Research Use Only

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