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NB-598

NB-598

Catalog Number:

L002368776APE

Mfr. No.:

APE-A3645

Price:

$444

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- Overview
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    Background
    
    NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.
- Properties
  - Alternative Name
    
    NB 598;NB598; (E)-N-(3-([3,3'-bithiophen]-5-ylmethoxy)benzyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine
    
    CAS Number
    
    131060-14-5
    
    Molecular Formula
    
    C27H31NOS2
    
    Molecular Weight
    
    449.67
    
    Appearance
    
    A brown oil
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥49.3 mg/mL in EtOH with gentle warming; ≥54 mg/mL in DMSO with gentle warming
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CCN(CC1=CC(OCC2=CC(C3=CSC=C3)=CS2)=CC=C1)C/C=C/C#CC(C)(C)C
    
    * For Research Use Only

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