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MZP-54

MZP-54

Catalog Number:
PTC1441525INV
Mfr. No.:
V3583
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      • Overview

        • MZP-54 is a novel, potent and selective PROTAC-based degrader of BRD3/4 with a Kd of 4 nM for Brd4BD2. The design of proteolysis-targeting chimeras (PROTACs) is a powerful small-molecule approach for inducing protein degradation. PROTACs conjugate a target warhead to an E3 ubiquitin ligase ligand via a linker.

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      • Properties
        • Categories
          PROTACs
          CAS Number
          2010159-47-2
          Molecular Formula
          C55H66CLN7O9S
          Molecular Weight
          1036.67
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          O=C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)C(C=C4)=CC=C4C5=CC6=C(C=C5)N(C(C)=O)[C@@H](C)C[C@H]6NC7=CC=C(Cl)C=C7

          * For research use only

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