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Overview
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Mycoplasma contamination is one of the most common and major problems in cell culture for research laboratories and industries. A conservative estimate states that around 15-35% of all continuous cell cultures are contaminated with mycoplasma. Mycoplasma is one type of the smallest and simplest self-replicating prokaryotes, which can’t be detected by visual inspection. It gradually affects cell growth and alters DNA, RNA, and protein synthesis of host cells.
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