Mouse tPA Genetically Deficient Spleen Lyophilized

Mouse tPA Genetically Deficient Spleen Lyophilized is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal, then lyophilized.

• Product Details

Species: Mouse

Antigen: tPA

Format: Lyophilized

Storage Conditions: 2°C to 8°C


• Mouse Model Details

Strain: C57BL6/SJL

Chromosome: 8

Gene: PLAT

Genomic Target: Exon 4

Mutation: 16 base pair deletion

Phenotype: Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA.

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