Mouse / Rat Testosterone ELISA

Testosterone is a sex steroid hormone from the androgen group synthesized by the Leydig cells in the testes in males, the ovaries in females, and adrenal glands in both sexes. It exerts a wide-ranging influence over sexual behaviour, muscle mass and strength, energy, cardiovascular health and bone integrity.
Several in vivo models including hormone-suppression, hormone-restoration and hypophysectomy were established for the study of the hormonal regulation of spermatogenesis by testosterone. In the Brown Norway rat, serum testosterone levels decrease with aging, accompanied by increases in serum FSH. The capacity of Leydig cells to produce testosterone is higher in young than in old rats. Testosterone secreted during late gestational and neonatal periods causes significant brain sexual dimorphism in the rat. This results in both sex-specific behaviour and endocrinology in adults.
Research area interests include androgen deficiency in males, Hirsutism, androgen excess, and drug toxicity, reprodtive functions, and Endocrine System Disruptors (ESDs).

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