Mouse / Rat Corticosterone ELISA

Corticosterone is the principle glucocorticoid secreted by the adrenal cortices of mice and rats. Secretion of corticosterone in these species is modulated by a complex negative feedback mechanism involving the central nervous system, hypothalamus, pituitary, and adrenals. ACTH released from the pituitary augments adrenal secretion of corticosterone while falling levels of corticosterone are associated with rising levels of ACTH. In both mice and rats there is a circadian rhythm of corticosterone release with the highest concentrations being observed between 1600 and 2200 hours in a normal laboratory environment.
Research area interests inslcude stress studies, circadian rhythm, endocrinology, metabolic diseases, obesity, and diabetes.

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