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Overview
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Predicted MW: Monomer, 9.2 kDa (83 aa). Macrophage inflammatory protein-3 beta (MIP-3 beta ), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3 beta signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3 beta also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs.
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Overview