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Overview
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Predicted MW: Monomer, 7.9 kDa (69 aa). Macrophage inflammatory protein-1 alpha (MIP-1 alpha), also known as CCL3, is a cytokine produced by macrophages. MIP-1 alpha binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 alpha and MIP-1 beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).
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