Name: MORF4L2 Polyclonal Antibody
Price: 253.00 USD

Overview
- Calculated MW: 32 kDa
  Observed MW: Refer to figures
  Gene Accession: NP036418
  
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  Background
  
  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthetic peptide of human MORF4L2
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.7 mg/mL
  
  Antigen
  
  KIAA0026 , MO4L2, MORF related gene X protein, MORF-related gene X protein, Morf4l2, MORFL2, Mortality factor 4 like protein 2, Mortality factor 4-like protein 2, MRGX, MSL3 2 protein, Protein MSL3-2, Transcription factor like protein MRGX , Transcription factor-like protein MRGX (UniProt:Q15014)
  
  * For reference only.