COX6A2 Polyclonal Antibody

COX6A2 Polyclonal Antibody

Catalog Number:
A001506232RED
Mfr. No.:
RD217847A
Price:
$253
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      • Overview
        • Calculated MW: 11 kDa
          Observed MW: Refer to figures
          Gene Accession: NP005196

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          Background

          Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide of human COX6A2
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.5 mg/mL
          Antigen
          COX VIa M, COX6AH, COXVIAH, Cytochrome c oxidase polypeptide VIa heart, Cytochrome c oxidase subunit 6A2 mitochondrial, Cytochrome c oxidase subunit VIA muscle, Cytochrome c oxidase subunit VIa polypeptide 2, MS411 (UniProt:Q02221)

          * For reference only.

      • Applications
        • Application
          WB; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          ELISA 1:5000-1:10000

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