Monocrotaline (Crotaline)

Monocrotaline (Crotaline)

Catalog Number:
L002438904INV
Mfr. No.:
V20396
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      • Overview
        • Monocrotaline (NSC-28693; Crotaline) is a naturally occuring pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant, exhibiting dose-dependent cytotoxicity and causing pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects. A

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      • Properties
        • Categories
          Disease Research Fields
          CAS Number
          315-22-0
          Molecular Formula
          C16H23NO6
          Molecular Weight
          325.36
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@@](C)(O)C3=O

          * For research use only

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