-
-
Overview
-
Monocrotaline (NSC-28693; Crotaline) is a naturally occuring pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant, exhibiting dose-dependent cytotoxicity and causing pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects. A
Please contact us at for specific academic pricing.
-
- Properties
-
Overview