Monoacetylphloroglucinol

- Overview
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    Background
    
    Monoacetylphloroglucinol (MAPG), small molecular weight phenolic metabolite, is produced via bacteria including Pseudomonas strains. MAPG is acetylated to form the broad-spectrum antibiotic, 2,4-diacetylphloroglucinol (DAPG) by MAPG acetyltransferase. In addition, MAPG exerts fairly weak potency when exhibiting a broad range of antibiotic activity. Even though weakly active, it seems that MAPG is essential in the biocontrol of plant diseases by some Pseudomonas strains [1]. In vitro: Up to now, in vitro study of MAPG is still in the development stage.In vivo: Up to now, in vivo study of MAPG is still in the development stage.
    
    [1]. HAYASHI, A., SAITOU, H., MORI, T., MATANO, I., SUGISAKI, H., & MARUYAMA, K. Molecular and Catalytic Properties of Monoacetylphloroglucinol Acetyltransferase fromPseudomonassp. YGJ3. Bioscience, Biotechnology, And Biochemistry. 2012; 76(3): 559-566.
- Properties
  - Categories
    
    broad range of antibiotic activity with fairly weak potency
    
    Alternative Name
    
    MAPG,NSC 54927,Phloroacetophenone,2',4',6'-Trihydroxyacetophenone; 1-(2,4,6-trihydroxyphenyl)-ethanone
    
    CAS Number
    
    480-66-0
    
    Molecular Formula
    
    C8H8O4
    
    Molecular Weight
    
    168.1
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥25.9 mg/mL in EtOH; ≥8.05 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    OC1=C(C(C)=O)C(O)=CC(O)=C1
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Datasheet

Monoacetylphloroglucinol

Background

Documents

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