MMP3 Antibody

MMP3 Antibody

Catalog Number:
A001547628IRE
Mfr. No.:
IR68-229s; IR68-229
Price:
$180
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      • Overview
        • Sensitivity: Endogenous
          Target name: MMP3
          Area: MMP remodeling

          Please contact us at for specific academic pricing.

          Background

          Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

      • Properties
        • Host
          Rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          Human
          Clone
          pAb
          Immunogen
          Synthetic peptide / encompassing a sequence within the center region
          Storage
          Store at +4°C for short term storage. Long time storage is recommended at -20°C
          100mM Tris Glycine, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
          Molecular Weight
          60

          * For research use only.

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          Western Blot 1:500
          Immunofluorescence 1: 100–1:200

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