Name: c-Myc Antibody [PK-9]
Price: 220.00 USD

Overview
- Sensitivity: Endogenous
  Target name: c-Myc antibody [PK-9]
  Area: Cancer oncology
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Properties
- Host
  
  Mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  Human
  
  Clone
  
  mAb
  
  Storage
  
  Store at +4°C for short term storage. Long time storage is recommended at -20°C
  Phosphate buffered solution, pH 7.2, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
  
  * For research use only.