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MMP 17 (MT4-MMP) catalytic domain, His-tagged

MMP 17 (MT4-MMP) catalytic domain, His-tagged

Catalog Number:
P001373811BIO
Mfr. No.:
30100402; 30100403
Price:
$755
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      • Overview

        • The catalytic domain of human MT4-MMP is produced by tryptic activation of a recombinant soluble proform purified from E. coli periplasm. Activation of progelatinase A; Degaradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          More than 80% of total protein
          Formulation
          The enzyme is solubilized in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.1% Triton X-100.
          Storage
          MT4-MMP is stable until the expiry date given on the label if stored at -70 °C. The enzyme can be kept at -20 °C for several weeks and at 4 °C for several days without significant loss of activity. Repeated freezing and thawing should be avoided.
          Molecular Weight
          21.7 kDa

          * For Research Use Only

      • Applications
        • Application Description
          Recombinant catalytic domain is used to study the biochemical function of MT4-MMP. The isolated enzyme allows screening of matrix metalloproteinase inhibitors and characterization of inhibitor action.
    Datasheet

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