MMP 24 (MT5-MMP) catalytic domain, His-tagged

MMP 24 (MT5-MMP) catalytic domain, His-tagged

Catalog Number:
P001373812BIO
Mfr. No.:
30100902; 30100903
Price:
$755
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      • Overview
        • The catalytic domain of human MT5-MMP is produced by activation of a recombinant soluble proform of MT5-MMP purified from E. coli periplasm. Activation of progelatinase A; Degaradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          The enzyme is solubilized in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2.
          Storage
          MT5-MMP is stable until the expiry date given on the label if stored at -70 °C. The enzyme can be kept at -20 °C for several weeks and in ice for one day without significant loss of activity. Repeated freezing and thawing should be avoided.
          Molecular Weight
          23 kDa

          * For Research Use Only

      • Applications
        • Application Description
          Recombinant catalytic domain of MT5-MMP is used to study the activation of progelatinase A (matrix metalloproteinase 2) and the degradation of proteins of the extracellular matrix. The enzyme allows screening of matrix metalloproteinase inhibitors and characterization of inhibitor action.

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