MLCK inhibitor peptide 18 , >95% by HPLC

MLCK inhibitor peptide 18 , >95% by HPLC

Catalog Number:
P004516861LIF
Mfr. No.:
PEPTIDE-KS-180
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  • Size:
    1mg
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      • Overview

        • Selective inhibitor of myosin light chain kinase.
          MLCK inhibitor peptide 18 is a selective cell permeable inhibitor of myosin light chain kinase with an IC50 of 50 nM. MLCK inhibitor peptide 18 displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. In vitro and in vivo treatment with the MLCK inhibitor peptide 18 attenuates the increased epithelial monolayer permeability and occludin endocytosis caused by intestinal anoxia/reoxygenation (A/R) injury.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          Myosin Light Chain Kinase Inhibitor Peptide 18, Peptide 18
          Molecular Formula
          C60H105N23O11
          Molecular Weight
          1324.64
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2,RKKYKYRRK-NH2
          Modification: C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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