ML133 HCl

ML133 HCl

Catalog Number:
L002370359APE
Mfr. No.:
APE-B2199
Price:
$145
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      • Overview
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          Background

          ML133 is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.

      • Properties
        • Alternative Name
          1-(4-methoxyphenyl)-N-(naphthalen-1-ylmethyl)methanamine;hydrochloride
          CAS Number
          1222781-70-5
          Molecular Formula
          C19H19NO·HCl
          Molecular Weight
          313.82
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥15.7 mg/mL in DMSO; ≥2.52 mg/mL in EtOH with gentle warming and ultrasonic
          Storage
          Store at -20°C

          * For Research Use Only

      • Reference
        • 1. NAN CAO, NIGALA AIKEREMU, et al. "Inhibition of KIR2. 1 decreases pulmonary artery smooth muscle cell proliferation and migration." Int J Mol Med. 2022 Sep;50(3):119. PMID: 35856410

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