MICU1 Polyclonal Antibody (0.6 mg/mL) for IHC, ELISA

MICU1 Polyclonal Antibody (0.6 mg/mL) for IHC, ELISA

Catalog Number:
A001508055RED
Mfr. No.:
RD252519A
Price:
$253
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      • Overview
        • Gene Accession: BC004190

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          Background

          This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
          MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human MICU1
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.6 mg/mL
          Antigen
          Allergen Hom s 4, ara CALC, atopy related autoantigen, atopy related autoantigen CALC, Atopy-related autoantigen CALC, CALC, calcium binding atopy related autoantigen 1, Calcium uptake protein 1, calcium uptake protein 1, mitochondrial, Calcium-binding atopy-related autoantigen 1, CBARA1, EFHA3, FLJ12684, MICU1, MICU1, mitochondrial, mitochondrial calcium uptake 1, MPXPS (UniProt:Q9BPX6)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:30-1:150
          ELISA 1:5000-1:10000

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