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Overview
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MDA-MB-231 cell line was metastatic human breast cancer cell line originally isolated from pleural effusions of a breast cancer patient in the early 1970s. MDA-MB-231 cells possess epithelial-like morphology and exhibit invasive properties when cultured in vitro and when transplanted into mice. MDA-MB-231 is widely used as a model for estrogen receptor negative breast cancer with applications in the study of tumorigenicity, metastasis, and cell invasion.
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Overview