mC5a1 ( IHC-grade ), Complement C5a Receptor 1 Polyclonal Antibody ( Mouse )

Overview
- The mouse C5a1 receptor antibody is directed against the distal end of the carboxyl-terminal tail of mouse and rat C5a1. It can be used to detect total C5a1 receptors in Western blots independent of phosphorylation. The mouse C5a1 antibody can also be used to isolate and enrich C5a1 receptors from cell and tissue lysates. It also detects C5a1 in cultured cells and tissue sections by immunohistochemistry. The mouse C5a1 antibody has been validated using knockout mice (KO-Validated).
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  mouse; rat
  
  Immunogen
  
  A synthetic peptide presents part of carboyl-terminal tail which is identical in mouse and rat C5a1
  
  Purification
  
  Antigen affinity chromatography
  
  Formulation
  
  Liquid
  
  Storage
  
  Short-term storage at 4°C and long-term storage at -20°C
  
  Antigen
  
  C5a1, C5AR1, Complement C5a Receptor 1, C5a Anaphylatoxin Chemotactic Receptor 1 (UniProt:P30993 (mouse), P97520 (rat))
  
  * This product is intended for research use only.

Applications

Application	Dilutions
Western Blot (WB)	1:1000
Immunohistochemistry (IHC)	1:100

Reference
- Nürge B, Schulz AL, Kaemmerer D, Sänger J, Evert K, Schulz S, Lupp A. Immunohistochemical identification of complement peptide C5a receptor 1 (C5aR1) in non-neoplastic and neoplastic human tissues. PLoS One. 2021 Feb 19;16(2):e0246939. doi: 10.1371/journal.pone.0246939. PMID: 33606748; PMCID: PMC7894821.