Name: Maytansinoid
Price: 532.00 USD

- Overview
  - Maytansine is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Antibody-maytansinoid conjugates consisting of maytansinoids (DM1 and DM4) attached to tumor-specific antibodies have shown promising clinical results.The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules.
    
    Please contact us at for specific academic pricing.
- Properties
  - Alternative Name
    
    MAYTANSINOL | 57103-68-1 | ZWJ9A2AJ2U | UNII-ZWJ9A2AJ2U | NSC-239386 | 3-o-De(2-(acetylmethylamino)-1-oxopropyl)maytansine | Maytansine, 3-o-de(2-(acetylmethylamino)-1-oxopropyl)- | (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14,4-dihydroxy-85,14-dimethoxy-33,2,7,10-
    
    CAS Number
    
    57103-68-1
    
    Molecular Formula
    
    C28H37ClN2O8
    
    Molecular Weight
    
    565.05
    
    Purity
    
    98%
    
    Other Properties
    
    Melt Point (°C): >153ºC (dec.)
    
    Storage
    
    Store at -20°C
    
    Shipping
    
    Dry ice
    
    SMILES
    
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)O)C)C)OC)(NC(=O)O2)O
    
    InChi
    
    InChI=1S/C28H37ClN2O8/c1-15-8-7-9-22(37-6)28(35)14-20(38-26(34)30-28)16(2)25-27(3,39-25)21(32)13-23(33)31(4)18-11-17(10-15)12-19(36-5)24(18)29/h7-9,11-12,16,20-22,25,32,35H,10,13-14H2,1-6H3,(H,30,34)/b9-7+,15-8+/t16-,20+,21+,22-,25+,27+,28+/m1/s1
    
    InChi Key
    
    QWPXBEHQFHACTK-RZKXNLMUSA-N
    
    PubChem CID
    
    9915934
    
    Others
    
    IUPAC Name: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione
    
    Hazard Information
    
    Signal: Danger
    Hazard Statements: H315,H319,H301,H311,H331,H314,H300,H310,H330,H340,H371
    Precautionary Statements: P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P284,P281,P271,P270,P301+P330+P331,P304+P340,P363,P403+P233,P362+P364,P330,P262,P320,P361+P364,P203,P264+P265,P301+P316,P305+P354+P338,P318,P337+P317,P308+P316,P332+P317,P302+P361+P354,P316
    
    * For research use only. Not for use in human or animal.

We Also Recommend

Maytansinoid AP-3

$774

MBS

$254

MBS

$774

MC (C5)-Val-Cit

$1,262