Mal-PEG4-Val-Cit-PAB-PNP

Mal-PEG4-Val-Cit-PAB-PNP

Catalog Number:
PG01492959ALA
Mfr. No.:
M596374-50mg; M596374-100mg; M596374-250mg
Price:
$771
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      • Overview
        • Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.

          Please contact us at for specific academic pricing.

      • Properties
        • CAS Number
          2112738-09-5
          Molecular Formula
          C40H53N7O15
          Molecular Weight
          871.9
          Purity
          97%
          Other Properties
          Solubility: Solubility in DMSO, DMF
          Storage
          Store at -20°C
          Shipping
          Dry ice
          SMILES
          CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCOCCOCCOCCOCCN3C(=O)C=CC3=O
          InChi
          InChI=1S/C40H53N7O15/c1-27(2)36(45-33(48)15-18-57-20-22-59-24-25-60-23-21-58-19-17-46-34(49)13-14-35(46)50)38(52)44-32(4-3-16-42-39(41)53)37(51)43-29-7-5-28(6-8-29)26-61-40(54)62-31-11-9-30(10-12-31)47(55)56/h5-14,27,32,36H,3-4,15-26H2,1-2H3,(H,43,51)(H,44,52)(H,45,48)(H3,41,42,53)/t32-,36-/m0/s1
          InChi Key
          ZEPYLTPLLQQBNX-IKYOIFQTSA-N
          PubChem CID
          129009586
          Others
          IUPAC Name: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate

          * For research use only. Not for use in human or animal.

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