Name: Magainin 1
Price: Inquiry

- Overview
  - Broad spectrum antimicrobial.
    Magainin 1 is a 23 amino acid amphipathic cationic peptide with broad-spectrum antimicrobial activities, originally extracted from the skin of the African clawed frog Xenopus laevis. Magainin 1 (and Magainin 2) are closely related hemolytic peptides which inhibit growth of bacteria by permeabilizing the cell membranes without significant toxicity against mammalian cells. The main target of magainin 1 and 2 is thought to be the lipid matrix of the membranes. Both magainin 1 and 2 are also cytotoxic to cancer cells and exhibit inhibitory action toward herpes simplex virus 1 and 2 (HSV 1 and 2).
    
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- Properties
  - Categories
    
    Antimicrobial Peptides
    
    Molecular Formula
    
    C112H177N29O28S
    
    Molecular Weight
    
    2409.8
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in dilute acid
    
    Other Properties
    
    Sequence: H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser-OH,GIGKFLHSAGKFGKAFVGEIMKS
    
    Storage
    
    Store frozen and desiccated in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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