Mag Oligo DT Magnetic Beads, mRNA Extraction, mRNA Purifcation

Oligo dT magnetic beads are magnetic microspheres covalently coated with oligodeoxythymine strands on their surface. Their core principle utilizes the base complementary pairing rule, where the Oligo dT strands specifically hybridize and bind to the PolyA tail, a characteristic feature at the 3' end of eukaryotic messenger RNA (mRNA), enabling the rapid and high-purity separation of mRNA from total RNA.
Simply put, Oligo dT magnetic beads act like a "specialized magnetic comb," precisely "extracting" mRNA with a PolyA tail from the RNA mixture.

Product Features
· High Specificity: Specifically binds to RNA with a PolyA tail, primarily mRNA, effectively removing interference from rRNA and tRNA (which constitute over 95% of total RNA).
· High Purity and Integrity: Gentle chemical reactions and non-alcoholic washing methods better preserve the integrity and purity of mRNA, making it suitable for downstream applications requiring extremely high RNA quality.
· Rapid and Simple Operation: The entire process can be completed within 30-60 minutes, significantly faster than the traditional oligo dT cellulose column chromatography method, and requires no centrifugation.
· High-Throughput Compatibility: Easily automated, compatible with 96-well plate formats, meeting the demands of high-throughput applications like sequencing.
· High Sensitivity: Suitable for mRNA isolation from trace samples (e.g., small numbers of cells, laser capture microdissected samples, FFPE sections).
· Safe and Environmentally Friendly: Avoids the use of toxic reagents like phenol and chloroform.

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