LRRKtide

LRRKtide

Catalog Number:
P004517023LIF
Mfr. No.:
PEPTIDE-KS-010
Price:
Inquiry
  • Size:
    1mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Leucine rich repeat kinase 2 (LRRK2) substrate.
          LRRKtide is a peptide substrate for leucine-rich repeat kinase 2 (LRRK2). The sequence of LRRKtide has been derived from the ERM protein family members ezrin (amino acids 561-573), radixin (amino acids 558-570) and moesin (amino acids 539-553), proteins which influence cytoskeletal dynamics by anchoring the cytoskeleton to the plasma membrane. LRRK2 phosphorylates LRRKtide at its Thr558 site. LRRK2 is found in most organs and is involved in several cellular pathways. The LRRK2 gene and α-synuclein gene (SNCA) are the key influencing factors of Parkinson’s disease (PD), with dysfunction of LRRK2 influencing the accumulation of α-synuclein.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Substrate Peptides
          Molecular Formula
          C83H147N31O22
          Molecular Weight
          1931.28
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in dilute acid
          Other Properties
          Sequence: H-Arg-Leu-Gly-Arg-Asp-Lys-Tyr-Lys-Thr-Leu-Arg-Gln-Ile-Arg-Gln-OH,RLGRDKYKTLRQIRQ
          Storage
          Store dark, frozen and desiccated

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

    We Also Recommend

    MBP (4-14)

    MBP (4-14)

    Phospho glycogen synthase peptide 2

    Phospho glycogen synthase peptide 2

    PKCδ Substrate

    PKCδ Substrate