Losartan

- Overview
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    Background
    
    Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
- Properties
  - Categories
    
    Angiotensin II receptor antagonist
    
    Alternative Name
    
    [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
    
    CAS Number
    
    114798-26-4
    
    Molecular Formula
    
    C22H23ClN6O
    
    Molecular Weight
    
    422.91
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    ≥2.48 mg/mL in H2O with gentle warming and ultrasonic; ≥2.9 mg/mL in EtOH with gentle warming; ≥84.6 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl
    
    * For Research Use Only