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Overview
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Background
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.
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Overview
LGR5/GPR49 Rabbit mAb
LGR5/GPR49 Rabbit mAb
Catalog Number:
A001550088RED
Mfr. No.:
RDSA66685
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.