[Leu144, Arg147]-PLP (139-151)

[Leu144, Arg147]-PLP (139-151)

Catalog Number:
P004516738LIF
Mfr. No.:
PEPTIDE-NR-040
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  • Size:
    1mg
    Quantity:
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      • Overview

        • T cell receptor antagonist.
          [Leu144, Arg147]-PLP (139-151) is an analogue of PLP (139-151) which can act as a T-cell receptor antagonist, able to prevent development of the autoimmune disease model experimental allergic encephalomyelitis (EAE). [Leu144, Arg147]-PLP (139-151 prevents EAE when co-administered with native PLP(139-151) and can limit progression of EAE if given early after the onset of disease in mice.

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      • Properties
        • Categories
          Myelin Peptides
          Molecular Formula
          C67H110N20O17
          Molecular Weight
          1467.7
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in dilute acid
          Other Properties
          Sequence: H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH,HSLGKLLGRPDKF
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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