Lentiviral human STING1 sgRNA gene knockout kit

Human STING1

Gene symbol: STING1
Synonyms: ERIS hMITA hSTING MITA MPYS NET23 SAVI STING STING-beta TMEM173
Species: HUMAN
Gene ID: 340061
Summary: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_198282:6:4