Lentiviral human RHOQ sgRNA gene knockout kit

Human RHOQ

Gene symbol: RHOQ
Synonyms: ARHQ HEL-S-42 RASL7A TC10 TC10A
Species: HUMAN
Gene ID: 23433
Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_012249:3:3