Lentiviral human RHOG sgRNA gene knockout kit

Human RHOG

Gene symbol: RHOG
Synonyms: ARHG
Species: HUMAN
Gene ID: 391
Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001665:2:1