Lentiviral human RASGRP2 sgRNA gene knockout kit

Human RASGRP2

Gene symbol: RASGRP2
Synonyms: CALDAG-GEFI CDC25L
Species: HUMAN
Gene ID: 10235
Summary: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_153819:9:8 NM_001098670:9:8 NM_001098671:9:8 NM_001318398:9:4